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Dermatopontin inhibits WNT signaling pathway via CXXC finger protein 4 in hepatocellular carcinoma

Dermatopontin inhibits WNT signaling pathway via CXXC finger protein 4 in hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is a serious reason behind tumor related deaths globally. Annually, the prevalence of HCC is rising and the dearth of early prognostic indicators manifests a dismal prognosis for HCC sufferers. A deep…

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Wnt-inducible Lrp6-APEX2 interacting proteins identify ESCRT machinery and Trk-fused gene as components of the Wnt signaling pathway

Wnt-inducible Lrp6-APEX2 interacting proteins identify ESCRT machinery and Trk-fused gene as components of the Wnt signaling pathway

The canonical Wnt pathway serves as a hub connecting numerous mobile processes, together with β-catenin signaling, differentiation, development, protein stability, macropinocytosis, and nutrient acquisition in lysosomes. We have proposed that sequestration of β-catenin destruction complicated…


Zinc Finger Protein CTCF Regulates Extracellular Matrix (ECM)-Related Gene Expression Associated With the Wnt Signaling Pathway in Gastric Cancer

Zinc Finger Protein CTCF Regulates Extracellular Matrix (ECM)-Related Gene Expression Associated With the Wnt Signaling Pathway in Gastric Cancer

Gastric most cancers (GC), a number one reason for cancer-related dying, is a heterogeneous illness. We intention to explain clinically related molecular classifications of GC that incorporate heterogeneity and supply helpful medical data. We mixed…