Computational design of antagonist peptides based on the structure of secreted frizzled-related protein-1 (SFRP1) aiming to inhibit Wnt signaling pathway
Aberrant activation of Wnt/β-catenin signaling pathway, due to the genetic or epigenetic modifications, is chargeable for tumorigenesis in epithelial cells of differing types of most cancers akin to colorectal most cancers. Secreted Frizzled-Related Protein-1 (SFRP1),…