Loss of mismatch repair signaling impairs the WNT-bone morphogenetic protein crosstalk and the colonic homeostasis.

Loss of mismatch repair signaling impairs the WNT-bone morphogenetic protein crosstalk and the colonic homeostasis.
Loss of mismatch repair signaling impairs the WNT-bone morphogenetic protein crosstalk and the colonic homeostasis.

The advantageous stability between proliferation, differentiation, and apoptosis in the colonic epithelium is tightly managed by the interaction between WNT, Notch, and bone morphogenetic protein (BMP) signaling. How these advanced networks coordinate the colonic homeostasis, particularly whether or not most cancers predisposing mutations comparable to mutations in the DNA mismatch repair (MMR) are current, is unclear. Inactivation of the MMR system has lengthy been linked to colorectal most cancers; nonetheless, little is understood about its function in the regulation of the colonic homeostasis. It has been proven that loss of MMR promotes the proliferation of colon epithelial cells that renders them extremely vulnerable to transformation.

The mechanism by which MMR mediates this impact, but, stays to be decided. Using a MMR-deficient mouse mannequin, we present that elevated methylation of Dickkopf1 (DKK1) impacts its expression, and consequently, the means to negatively regulate WNT signaling. As a consequence, extreme ranges of lively β-catenin promote sturdy crypt progenitor-like phenotype and irregular proliferation. Under these settings, the growth and operate of the goblet cells are affected. MMR-deficient mice have fewer goblet cells with enlarged mucin-loaded vesicles. We additional present that MMR inactivation impacts the WNT-BMP signaling crosstalk. Thromboembolism is a generally noticed situation in geriatrics that’s brought on by vascular endothelial harm, platelet activation, physiological coagulation processes, discount of anticoagulant exercise, decreased fibrinolytic exercise and irregular stream in the coronary heart chamber, artery or vein.

The protein C anticoagulant system serves a vital function in anticoagulant remedy for the therapy of thromboembolism. Previous findings have advised that edoxaban is an environment friendly oral anticoagulant in the acute therapy of venous thromboembolism. In the current examine, the efficacy of edoxaban on thromboembolism induced by atrial fibrillation was investigated in a mouse mannequin. Inflammatory components interleukin (IL)-1, -4, -8 and tumor necrosis issue (TNF)-α have been analyzed in the sera of mice with fibrillation induced by thromboembolism.

Wnt canonical pathway prompts macropinocytosis and lysosomal degradation of extracellular proteins.

Canonical Wnt signaling is rising as a serious regulator of endocytosis. Wnt therapy markedly elevated the endocytosis and degradation in lysosomes of BSA. In this examine, we report that along with receptor-mediated endocytosis, Wnt additionally triggers the consumption of giant quantities of extracellular fluid by macropinocytosis, a nonreceptor-mediated actin-driven course of. Macropinocytosis induction is fast and impartial of protein synthesis. In the presence of Wnt, giant quantities of nutrient-rich packages comparable to proteins and glycoproteins have been channeled into lysosomes after fusing with smaller receptor-mediated vesicles containing glycogen synthase kinase 3 (GSK3) and protein arginine ethyltransferase 1 (PRMT1), an enzyme required for canonical Wnt signaling.
Addition of Wnt3a, in addition to overexpression of Disheveled (Dvl), Frizzled (Fz8), or dominant-negative Axin induced endocytosis. Depletion of the tumor suppressors adenomatous polyposis coli (APC) or Axin dramatically elevated macropinocytosis, outlined by incorporation of the excessive molecular weight marker tetramethylrhodamine (TMR)-dextran and its blockage by the Na+/H+ exchanger ethylisopropyl amiloride (EIPA). Macropinocytosis was blocked by dominant-negative vacuolar protein sorting 4 (Vps4), indicating that the Wnt pathway relies on multivesicular physique formation, a course of known as microautophagy.

SW480 colorectal most cancers cells displayed constitutive macropinocytosis and elevated extracellular protein degradation in lysosomes, which have been suppressed by restoring full-length APC. Accumulation of the transcriptional activator β-catenin in the nucleus of SW480 cells was inhibited by methyltransferase inhibition, EIPA, or the diuretic amiloride. The outcomes point out that Wnt signaling switches metabolism towards nutrient acquisition by engulfment of extracellular fluids and recommend doable therapies for Wnt-driven most cancers development.

 Loss of mismatch repair signaling impairs the WNT-bone morphogenetic protein crosstalk and the colonic homeostasis.

Loss of mismatch repair signaling impairs the WNT-bone morphogenetic protein crosstalk and the colonic homeostasis.

Wnt/β-Catenin Signaling Pathway-Related Proteins (DKK-3, β-Catenin, and c-MYC) Are Involved in Prognosis of Nasopharyngeal Carcinoma.

The Wnt/β-catenin signaling pathway is one of the extremely conserved signaling pathway broadly reported to play important roles in the growth of varied tumors and human cancers, thus serving as a possible goal for anticancer remedy. However, the particular results of the associated proteins in the Wnt/β-catenin signaling pathway in nasopharyngeal carcinoma (NPC) nonetheless stay elusive. Thus, this examine was carried out to uncover the correlation between the Wnt/β-catenin signaling pathway-related proteins and the scientific traits and prognosis of NPC. NPC tissues have been revealed to current excessive expression of β-catenin and v-myc myelocytomatosis viral oncogene homolog (c-MYC) however low expression of Dickkopf-3 (DKK-3).
Immunohistochemical staining revealed that DKK-Three was positively linked to however β-catenin and c-MYC have been negatively linked to differentiation, tumor-node-metastasis (TNM) stage and lymph node metastasis of sufferers with NPC. In addition, c-MYC was recognized to be positively correlated to DKK-Three in NPC tissues. The optimistic expression of β-catenin and c-MYC had detrimental relations with and that of DKK-Three had optimistic relations with survival fee of sufferers with NPC, which was analyzed by Kaplan-Meier methodology.
Crystallin Beta B3 antibody
70R-2830 50 ug
EUR 467
Description: Rabbit polyclonal Crystallin Beta B3 antibody raised against the middle region of CRYBB3
Crystallin beta B1 Protein
20-abx260553
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  • EUR 328.00
  • EUR 230.00
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Crystallin beta A4 Protein
20-abx260794
  • EUR 3418.00
  • EUR 328.00
  • EUR 230.00
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anti-Beta crystallin S
YF-PA11110 50 ul
EUR 363
Description: Mouse polyclonal to Beta crystallin S
anti-Beta crystallin S
YF-PA11111 50 ug
EUR 363
Description: Mouse polyclonal to Beta crystallin S
anti-beta Crystallin A3
YF-PA23513 50 ul
EUR 334
Description: Mouse polyclonal to beta Crystallin A3
anti-beta B1 Crystallin
YF-PA23515 50 ul
EUR 334
Description: Mouse polyclonal to beta B1 Crystallin
Recombinant Human Crystallin Beta B1
7-06919 5µg Ask for price
Recombinant Human Crystallin Beta B1
7-06920 25µg Ask for price
Recombinant Human Crystallin Beta B1
7-06921 1mg Ask for price
Recombinant Human Crystallin Beta A4
7-06922 5µg Ask for price
Recombinant Human Crystallin Beta A4
7-06923 20µg Ask for price
Recombinant Human Crystallin Beta A4
7-06924 1mg Ask for price
Crystallin Beta B3 Blocking Peptide
33R-5223 100 ug
EUR 180
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of CRYBB3 antibody, catalog no. 70R-2830
Crystallin Beta A1 Blocking Peptide
33R-5973 100 ug
EUR 180
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of CRYBA1 antibody, catalog no. 70R-2029
Human beta B1 Crystallin Antibody
33007-05111 150 ug
EUR 261
Human Beta-crystallin S (CRYGS
1-CSB-EP006025HU
  • EUR 380.00
  • EUR 214.00
  • EUR 1309.00
  • EUR 560.00
  • EUR 873.00
  • EUR 262.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
  • MW: 47.9 kDa
  • Buffer composition: Tris-based buffer with 50% glycerol.
Description: Recombinant Human Beta-crystallin S(CRYGS expressed in E.coli
Crystallin Beta A1 (CRYBA1) Antibody
abx026765-400ul 400 ul
EUR 523
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Crystallin Beta A1 (CRYBA1) Antibody
abx026765-80l 80 µl
EUR 286
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Crystallin Beta B1 (CRYbB1) Antibody
20-abx102005
  • EUR 453.00
  • EUR 133.00
  • EUR 1302.00
  • EUR 620.00
  • EUR 342.00
  • 100 ug
  • 10 ug
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  • 50 ug
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Crystallin Beta B2 (CRYbB2) Antibody
20-abx102006
  • EUR 439.00
  • EUR 133.00
  • EUR 1233.00
  • EUR 592.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
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Crystallin Beta B2 (CRYbB2) Antibody
20-abx102007
  • EUR 356.00
  • EUR 913.00
  • EUR 467.00
  • EUR 154.00
  • EUR 272.00
  • 100 ug
  • 1 mg
  • 200 ug
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Crystallin Beta B1 (CRYBB1) Antibody
20-abx111823
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  • EUR 398.00
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Crystallin Beta B3 (CRYBB3) Antibody
20-abx111824
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  • EUR 398.00
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Crystallin Beta A1 (CRYbA1) Antibody
20-abx129439
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  • EUR 133.00
  • EUR 1233.00
  • EUR 592.00
  • EUR 328.00
  • 100 ug
  • 10 ug
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Crystallin Beta B1 (CRYbB1) Antibody
20-abx129440
  • EUR 439.00
  • EUR 133.00
  • EUR 1233.00
  • EUR 592.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.
Crystallin Beta B2 (CRYbB2) Antibody
20-abx132152
  • EUR 356.00
  • EUR 133.00
  • EUR 1024.00
  • EUR 509.00
  • EUR 300.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-12 working days.
Crystallin Beta B3 (CRYBB3) Antibody
abx145035-100ug 100 ug
EUR 391
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Crystallin Beta B1 (CRYBB1) Antibody
abx145066-100ug 100 ug
EUR 391
  • Shipped within 5-10 working days.
Crystallin Beta A1 (CRYBA1) Antibody
abx145287-100ug 100 ug
EUR 391
  • Shipped within 5-10 working days.
Crystallin Beta A2 (CRYBA2) Antibody
abx145550-100ug 100 ug
EUR 391
  • Shipped within 5-10 working days.
Crystallin Beta A1 (CRYBA1) Antibody
20-abx318504
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.
Crystallin Beta B1 (CRYBB1) Antibody
20-abx322355
  • EUR 439.00
  • EUR 328.00
  • 100 ul
  • 50 ul
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Crystallin Beta A2 (CRYBA2) Antibody
abx232000-100ug 100 ug
EUR 481
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Crystallin Beta B1 (CRYBB1) Antibody
abx232001-100ug 100 ug
EUR 481
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Crystallin Beta B1 (CRYBB1) Antibody
abx232002-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.
Crystallin Beta B2 (CRYBB2) Antibody
abx232003-100ug 100 ug
EUR 481
  • Shipped within 5-12 working days.
Crystallin Beta B3 (CRYBB3) Antibody
abx232004-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.
Crystallin Beta B2 (CRYBB2) Antibody
20-abx000083
  • EUR 411.00
  • EUR 592.00
  • EUR 182.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul
  • Shipped within 5-10 working days.
Recombinant Crystallin Beta A1 (CRYbA1)
4-RPF342Mu01
  • EUR 494.24
  • EUR 235.00
  • EUR 1578.40
  • EUR 592.80
  • EUR 1085.60
  • EUR 394.00
  • EUR 3796.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
  • Uniprot ID: P02525
  • Buffer composition: PBS, pH 7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
  • Form: Freeze-dried powder
  • Predicted Molecular Mass (KD): 28.9kDa
  • Isoelectric Point: Inquire
Description: Recombinant Mouse Crystallin Beta A1 expressed in: E.coli
Recombinant Crystallin Beta B1 (CRYbB1)
4-RPF345Mu01
  • EUR 494.24
  • EUR 235.00
  • EUR 1578.40
  • EUR 592.80
  • EUR 1085.60
  • EUR 394.00
  • EUR 3796.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
  • Uniprot ID: Q9WVJ5
  • Buffer composition: PBS, pH 7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
  • Form: Freeze-dried powder
  • Predicted Molecular Mass (KD): 49.9kDa
  • Isoelectric Point: Inquire
Description: Recombinant Mouse Crystallin Beta B1 expressed in: E.coli
Recombinant Crystallin Beta B1 (CRYbB1)
4-RPF345Ra01
  • EUR 404.64
  • EUR 211.00
  • EUR 1242.40
  • EUR 480.80
  • EUR 861.60
  • EUR 334.00
  • EUR 2956.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
  • Uniprot ID: Inquire
  • Buffer composition: PBS, pH 7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
  • Form: Freeze-dried powder
  • Predicted Molecular Mass (KD): 21.3kDa
  • Isoelectric Point: Inquire
Description: Recombinant Rat Crystallin Beta B1 expressed in: E.coli
Recombinant Crystallin Beta B2 (CRYbB2)
4-RPF346Mu01
  • EUR 413.60
  • EUR 214.00
  • EUR 1276.00
  • EUR 492.00
  • EUR 884.00
  • EUR 340.00
  • EUR 3040.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
  • Uniprot ID: P62696
  • Buffer composition: 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
  • Form: Freeze-dried powder
  • Predicted Molecular Mass (KD): 21.3kDa
  • Isoelectric Point: 6.6
Description: Recombinant Mouse Crystallin Beta B2 expressed in: E.coli
Recombinant Crystallin Beta B2 (CRYbB2)
4-RPF346Ra01
  • EUR 413.60
  • EUR 214.00
  • EUR 1276.00
  • EUR 492.00
  • EUR 884.00
  • EUR 340.00
  • EUR 3040.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
  • Uniprot ID: Inquire
  • Buffer composition: PBS, pH 7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
  • Form: Freeze-dried powder
  • Predicted Molecular Mass (KD): 21.3kDa
  • Isoelectric Point: 6.4
Description: Recombinant Rat Crystallin Beta B2 expressed in: E.coli
Anti-Beta crystallin S Antibody
STJ500306 100 µg
EUR 476
Anti-Beta crystallin S Antibody
STJ500307 100 µg
EUR 476
Anti-beta B1 Crystallin (2B2)
YF-MA12542 100 ug
EUR 363
Description: Mouse monoclonal to beta B1 Crystallin
Anti-beta B1 Crystallin (3D9)
YF-MA12543 100 ug
EUR 363
Description: Mouse monoclonal to beta B1 Crystallin
Mouse Crystallin Beta A1 (CRYbA1) Protein
20-abx167367
  • EUR 690.00
  • EUR 286.00
  • EUR 2124.00
  • EUR 815.00
  • EUR 495.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.
Mouse Crystallin Beta B1 (CRYbB1) Protein
20-abx167368
  • EUR 690.00
  • EUR 286.00
  • EUR 2124.00
  • EUR 815.00
  • EUR 495.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.
Rat Crystallin Beta B1 (CRYbB1) Protein
20-abx066155
  • EUR 578.00
  • EUR 258.00
  • EUR 1678.00
  • EUR 676.00
  • EUR 425.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-15 working days.
Mouse Crystallin Beta B2 (CRYbB2) Protein
20-abx066156
  • EUR 578.00
  • EUR 258.00
  • EUR 1720.00
  • EUR 690.00
  • EUR 425.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.
Crystallin Beta B2 (CRYbB2) Antibody (Biotin)
20-abx273014
  • EUR 467.00
  • EUR 244.00
  • EUR 1344.00
  • EUR 634.00
  • EUR 342.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-15 working days.
Crystallin Beta B1 (CRYbB1) Antibody (Biotin)
20-abx273350
  • EUR 481.00
  • EUR 244.00
  • EUR 1414.00
  • EUR 662.00
  • EUR 356.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-15 working days.
Rat Crystallin Beta B2 (CRYbB2) Protein
20-abx652230
  • EUR 578.00
  • EUR 258.00
  • EUR 1720.00
  • EUR 690.00
  • EUR 425.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.
Crystallin Beta A1 (CRYBA1) Antibody (HRP)
20-abx303503
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.
Crystallin Beta A1 (CRYBA1) Antibody (FITC)
20-abx303504
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.
Crystallin Beta A1 (CRYBA1) Antibody (Biotin)
20-abx303505
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.
Anti-Beta crystallin S Antibody BIOTIN
STJ500308 100 µg
EUR 586
Anti-Beta crystallin S Antibody FITC
STJ500309 100 µg
EUR 586
Anti-Beta crystallin S Antibody BIOTIN
STJ500310 100 µg
EUR 586
Anti-Beta crystallin S Antibody FITC
STJ500311 100 µg
EUR 586
Human beta B1 Crystallin Antibody (Biotin Conjugate)
33007-05121 150 ug
EUR 369
Mouse Crystallin Beta A1 (CRYBA1) ELISA Kit
20-abx156974
  • EUR 7378.00
  • EUR 3933.00
  • EUR 911.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests
  • Shipped within 5-7 working days.
Mouse Crystallin Beta B1 (CRYBB1) ELISA Kit
20-abx156975
  • EUR 7378.00
  • EUR 3933.00
  • EUR 911.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests
  • Shipped within 5-7 working days.
Mouse Crystallin Beta B2 (CRYBB2) ELISA Kit
20-abx156976
  • EUR 7378.00
  • EUR 3933.00
  • EUR 911.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests
  • Shipped within 5-7 working days.
Rat Crystallin Beta B2 (CRYBB2) ELISA Kit
20-abx258828
  • EUR 7237.00
  • EUR 3855.00
  • EUR 895.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests
  • Shipped within 5-7 working days.
Human Crystallin Beta B2 (CRYBB2) ELISA Kit
20-abx258829
  • EUR 7378.00
  • EUR 3933.00
  • EUR 911.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests
  • Shipped within 5-7 working days.
Bovine Beta- crystallin A3, CRYBA1 ELISA KIT
ELI-09074b 96 Tests
EUR 928
Human Beta- crystallin A4, CRYBA4 ELISA KIT
ELI-09075h 96 Tests
EUR 824
Mouse Beta- crystallin S, Crygs ELISA KIT
ELI-09076m 96 Tests
EUR 865
Rabbit Beta- crystallin S, CRYGS ELISA KIT
ELI-09077Ra 96 Tests
EUR 928
Bovine Beta- crystallin B3, CRYBB3 ELISA KIT
ELI-09324b 96 Tests
EUR 928
Human Beta- crystallin A3, CRYBA1 ELISA KIT
ELI-10438h 96 Tests
EUR 824
Chicken Beta- crystallin A2, CRYBA2 ELISA KIT
ELI-10439c 96 Tests
EUR 928
Porcine Beta- crystallin B1, CRYBB1 ELISA KIT
ELI-10440p 96 Tests
EUR 928
Mouse Beta- crystallin A1, Cryba1 ELISA KIT
ELI-10489m 96 Tests
EUR 865
Mouse Beta- crystallin A4, Cryba4 ELISA KIT
ELI-10490m 96 Tests
EUR 865
Human Beta- crystallin B3, CRYBB3 ELISA KIT
ELI-10492h 96 Tests
EUR 824
Chicken Beta- crystallin A3, CRYBA1 ELISA KIT
ELI-25556c 96 Tests
EUR 928
Human Beta- crystallin B2, CRYBB2 ELISA KIT
ELI-25689h 96 Tests
EUR 824
Bovine Beta- crystallin A4, CRYBA4 ELISA KIT
ELI-26111b 96 Tests
EUR 928
Mouse Beta- crystallin B2, Crybb2 ELISA KIT
ELI-26113m 96 Tests
EUR 865
Human Beta- crystallin A2, CRYBA2 ELISA KIT
ELI-26435h 96 Tests
EUR 824
Bovine Beta- crystallin B2, CRYBB2 ELISA KIT
ELI-26436b 96 Tests
EUR 928
Chicken Beta- crystallin B2, CRYBB2 ELISA KIT
ELI-26437c 96 Tests
EUR 928
Mouse Beta- crystallin B3, Crybb3 ELISA KIT
ELI-26438m 96 Tests
EUR 865
Human Beta- crystallin S, CRYGS ELISA KIT
ELI-26440h 96 Tests
EUR 824
Rabbit Beta- crystallin A2, CRYBA2 ELISA KIT
ELI-46668Ra 96 Tests
EUR 928
Mouse Crystallin Beta A1 (CRYbA1) CLIA Kit
20-abx494872
  • EUR 7973.00
  • EUR 4246.00
  • EUR 981.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests
  • Please enquire.
Mouse Crystallin Beta B1 (CRYbB1) CLIA Kit
20-abx494873
  • EUR 7973.00
  • EUR 4246.00
  • EUR 981.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests
  • Please enquire.
Mouse Crystallin Beta B2 (CRYbB2) CLIA Kit
20-abx494874
  • EUR 7973.00
  • EUR 4246.00
  • EUR 981.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests
  • Please enquire.
Human Crystallin Beta B2 (CRYbB2) CLIA Kit
20-abx496401
  • EUR 7973.00
  • EUR 4246.00
  • EUR 981.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests
  • Please enquire.
Rat Crystallin Beta B2 (CRYbB2) CLIA Kit
20-abx496506
  • EUR 8569.00
  • EUR 4560.00
  • EUR 1052.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests
  • Please enquire.
Human Crystallin Beta A2 (CRYBA2) ELISA Kit
abx386685-96tests 96 tests
EUR 911
  • Shipped within 5-12 working days.
Human Crystallin Beta B1 (CRYBB1) ELISA Kit
abx386686-96tests 96 tests
EUR 911
  • Shipped within 5-12 working days.
Human Crystallin Beta B3 (CRYBB3) ELISA Kit
abx386688-96tests 96 tests
EUR 911
  • Shipped within 5-12 working days.
Moreover, it was proven that later TNM stage and optimistic expression of β-catenin have been threat components for NPC-related dying. These findings present proof that the proteins associated to the Wnt/β-catenin signaling pathway (DKK-3, β-catenin, and c-MYC) take part in the growth of NPC and optimistic expression of DKK-3 and detrimental expression of β-catenin, and c-MYC can function important prognostic biomarkers, shedding new gentle on the prognosis and therapy of NPC.