Ark shell protein-derived bioactive peptides promote osteoblastic differentiation through upregulation of the canonical Wnt/β-catenin signaling in human bone marrow-derived mesenchymal stem cells

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Ark shell protein-derived bioactive peptides promote osteoblastic differentiation through upregulation of the canonical Wnt/β-catenin signaling in human bone marrow-derived mesenchymal stem cells

Posted By: Judith Reynolds May 28, 2021

In this research, the stimulating impact of ark shell protein-derived peptides AWLNH and PHDL on osteoblast differentiation in human bone marrow-derived mesenchymal stem cells (hBMMSCs) and its molecular mechanism was investigated. The hBMMSCs have been cultured with two peptides and osteogenic markers have been analyzed. Results confirmed that enhanced ALP exercise and calcification have been detected in the presence of AWLNH and PHDL.
Based on western blotting, RT-qPCR, and immunostaining evaluation, AWLNH and PHDL are particular for osteoblast differentiation of hBMMSCs through activating the canonical Wnt/β-catenin signaling pathway adopted by activating Runx2, osterix, and kind I collagen. Loss-of-function assay with DKK-1, a Wnt antagonist, confirmed that the canonical Wnt/β-catenin signaling was important for AWLNH and PHDL-induced osteogenesis in hBMMSCs.
These findings steered that AWLNH and PHDL can stimulate osteoblast differentiation of hBMMSCs by way of upregulating the canonical Wnt/β-catenin signaling and could also be helpful for a possible nutraceuticals or prescription drugs to deal with osteoporosis. PRACTICAL APPLICATIONS: Ark shell is a well-liked foodstuff in Korea. However, organic results of its protein and peptide haven’t been explored in some ways. This research demonstrated that ark shell protein-derived peptides promoted osteoblast differentiation in hBMMSCs through upregulating the canonical Wnt/β-catenin signaling. The outcomes of this research may very well be a foundation to promote its utility as practical meals and/or nutraceuticals.

Wnts regulate planar cell polarity by way of heterotrimeric G protein and PI3K signaling

In the mammalian cochlea, the planar cell polarity (PCP) pathway aligns hair cell orientation alongside the aircraft of the sensory epithelium. Concurrently, a number of cell intrinsic planar polarity (known as iPCP) modules mediate planar polarization of the hair cell apical cytoskeleton, together with the kinocilium and the V-shaped hair bundle important for mechanotransduction. How PCP and iPCP are coordinated throughout growth and the roles of Wnt ligands in this course of stay unresolved. Here we present that genetic blockade of Wnt secretion in the cochlear epithelium resulted in a shortened cochlear duct and misoriented and misshapen hair bundles.
Mechanistically, Wnts stimulate Gi exercise by regulating the localization of Daple, a guanine nucleotide alternate issue (GEF) for Gαi. In flip, the Gβγ advanced alerts through phosphoinositide 3-kinase (PI3K) to manage kinocilium positioning and uneven localizations of a subset of core PCP proteins, thereby coordinating PCP and iPCP. Thus, our outcomes establish a putative Wnt/heterotrimeric G protein/PI3K pathway for PCP regulation.

H. pylori slyD, a novel virulence issue, is related to Wnt pathway protein expression throughout gastric illness development

We have beforehand reported that the virulence issue HpslyD is said to the prevalence of gastric illnesses. However, its mechanism of pathogenesis remains to be unclear. It is often believed that the Wnt/β-catenin pathway is indispensable for the growth of gastric most cancers, however it’s unclear whether or not HpslyD and Wnt/β-catenin work together throughout the growth of gastric illnesses.
Therefore, we measured the expression of E-cadherin, β-catenin, TCF4, and CDX2 proteins by IHC in gastric mucosa specimens from sufferers with totally different gastric illnesses and in contrast the variations in protein expression to H. pylori-infection standing. The outcomes indicated that the expression of these proteins was related to HpslyD an infection. HpslyD subtype an infection, slightly than widespread H. pylori an infection, might have a better impact on the expression of Wnt proteins in atrophic gastritis and gastric most cancers.
Additionally, HpslyD pressure an infection promoted the expression of Wnt pathway-related proteins with the development of gastric illness. This research offers perception into the pathogenesis of H. pylori-related gastric illnesses and “type-based remedy” for H. pylori an infection.

Liraglutide suppresses manufacturing of extracellular matrix proteins and ameliorates renal harm of diabetic nephropathy by enhancing Wnt/β-catenin signaling

The Wnt/β-catenin signaling pathway is concerned in the manufacturing of extracellular matrix (ECM) by mesangial cells (MCs). Recent research by us and others demonstrated that glucagon-like peptide-1 receptor agonists (GLP-1RAs) have protecting results in opposition to diabetic nephropathy. The goal of this research was to research whether or not the Wnt/β-catenin signaling in MCs contributed to GLP-1RA-induced inhibition of ECM accumulation and mitigation of glomerular harm in diabetic nephropathy. In cultured human mesangial cells (HMCs), liraglutide (a GLP-1RA) remedy considerably decreased excessive glucose (HG)-stimulated manufacturing of fibronectin (FN), collagen IV (Col IV) and α-smooth muscle actin (α-SMA) and the liraglutide results have been considerably attenuated by XAV-939, a selective inhibitor of the Wnt/β-catenin signaling. Furthermore, HG remedy considerably decreased the protein abundance of Wnt4, Wnt5a, phospho-glycogen synthase kinase-3β and β-catenin.
These HG results on the Wnt/β-catenin signaling proteins have been considerably blunted by liraglutide remedy. For in vivo research, we administered liraglutide (200μg/kg/12h) by subcutaneous injection to streptozocin-induced kind 1 diabetic rats for eight weeks. Administration of liraglutide considerably improved elevated blood urine nitrogen, serum creatinine, and urinary albumin excretion price, and alleviated renal hypertrophy, mesangial enlargement, and glomerular fibrosis in kind 1 diabetic rats whereas blood glucose degree and physique weight didn’t have important modifications.
Consistent with the in vitro research, liraglutide remedy considerably decreased the diabetes-induced will increase in glomerular FN, Col IV and α-SMA, and reduces in glomerular Wnt/β-catenin signaling proteins. These outcomes counsel that liraglutide alleviated glomerular ECM accumulation and renal harm in diabetic nephropathy by enhancing the Wnt/β-catenin signaling.
Ark shell protein-derived bioactive peptides promote osteoblastic differentiation through upregulation of the canonical Wnt/β-catenin signaling in human bone marrow-derived mesenchymal stem cells

Transmembrane protein 88 exerts a tumor-inhibitory position in thyroid most cancers through restriction of Wnt/β-catenin signaling

Transmembrane protein 88 (TMEM88) has emerged as a newly found cancer-related protein that acts as a cancer-promoting or cancer-inhibiting regulator in a number of tumor varieties. However, the actual position of TMEM88 in thyroid most cancers is undetermined. The present research was designed to find out the expression, perform, and potential underlying mechanism of TMEM88 in thyroid most cancers. Our knowledge demonstrated low TMEM88 expression in thyroid most cancers tissues.
Decreased TMEM88 expression was additionally discovered in a number of thyroid most cancers cell traces, and restoration of TMEM88 markedly suppressed the proliferation, colony formation, and invasive potential of thyroid most cancers cells. On the opposite, TMEM88 depletion considerably accelerated the proliferation, colony formation, and invasion of thyroid most cancers cells. Further experiments documented that TMEM88 overexpression markedly decreased the expression of the energetic kind of β-catenin and inhibited the expression of Wnt/β-catenin signaling targets genes, corresponding to c-myc and cyclin D1.
Notably, reactivation of Wnt/β-catenin signaling by transfecting a vector that expressed constitutively energetic β-catenin partially reversed the TMEM88-mediated suppressive impact on thyroid most cancers cell proliferation and invasion. In addition, TMEM88 upregulation markedly retarded the tumor development of thyroid most cancers cells in vivo utilizing xenograft fashions related to downregulation of energetic β-catenin expression. Taken collectively, our findings demonstrated that TMEM88 overexpression impeded the proliferation and invasion of thyroid most cancers cells through downregulation of Wnt/β-catenin signaling.

Nuclear pore complex protein Nup153 Antibody (HRP)
20-abx108567
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Recombinant human Nuclear pore complex protein Nup133
P2220 100ug Ask for price
Description: Recombinant protein for human Nuclear pore complex protein Nup133

CPN1 Antibod
34550-100ul 100ul
EUR 252

CPN1 Antibod
34550-50ul 50ul
EUR 187

CDYLy2 Antibod
34590-100ul 100ul
EUR 252

CDYLy2 Antibod
34590-50ul 50ul
EUR 187

Human Nuclear pore complex protein Nup155, NUP155 ELISA KIT
ELI-15040h 96 Tests
EUR 824

Mouse Nuclear pore complex protein Nup50, Nup50 ELISA KIT
ELI-15055m 96 Tests
EUR 865

Human Nuclear pore complex- interacting protein, NPIP ELISA KIT
ELI-16689h 96 Tests
EUR 824

Mouse Nuclear pore complex protein Nup54, Nup54 ELISA KIT
ELI-21319m 96 Tests
EUR 865

Mouse Nuclear pore complex protein Nup160, Nup160 ELISA KIT
ELI-21357m 96 Tests
EUR 865

Mouse Nuclear pore complex protein Nup214, Nup214 ELISA KIT
ELI-21358m 96 Tests
EUR 865

Human Nuclear pore complex protein Nup50, NUP50 ELISA KIT
ELI-22432h 96 Tests
EUR 824

Bovine Nuclear pore complex protein Nup85, NUP85 ELISA KIT
ELI-23491b 96 Tests
EUR 928

Mouse Nuclear pore complex protein Nup85, Nup85 ELISA KIT
ELI-23492m 96 Tests
EUR 865

Mouse Nuclear pore complex protein Nup155, Nup155 ELISA KIT
ELI-44221m 96 Tests
EUR 865

Human Nuclear pore complex protein Nup214, NUP214 ELISA KIT
ELI-44222h 96 Tests
EUR 824

Bovine Nuclear pore complex protein Nup93, NUP93 ELISA KIT
ELI-44229b 96 Tests
EUR 928

Mouse Nuclear pore complex protein Nup133, Nup133 ELISA KIT
ELI-44499m 96 Tests
EUR 865

Mouse Nuclear pore complex protein Nup93, Nup93 ELISA KIT
ELI-44561m 96 Tests
EUR 865

Human Nuclear pore complex protein Nup153, NUP153 ELISA KIT
ELI-44867h 96 Tests
EUR 824

Human Nuclear pore complex protein Nup133, NUP133 ELISA KIT
ELI-46087h 96 Tests
EUR 824

Mouse Nuclear pore complex protein Nup88, Nup88 ELISA KIT
ELI-35536m 96 Tests
EUR 865

Mouse Nuclear pore complex protein Nup107, Nup107 ELISA KIT
ELI-38239m 96 Tests
EUR 865

Human Nuclear pore complex protein Nup160, NUP160 ELISA KIT
ELI-38240h 96 Tests
EUR 824

Human Nuclear pore complex protein Nup205, NUP205 ELISA KIT
ELI-38242h 96 Tests
EUR 824

Human Nuclear pore complex protein Nup85, NUP85 ELISA KIT
ELI-36779h 96 Tests
EUR 824

Human Nuclear pore complex protein Nup88, NUP88 ELISA KIT
ELI-36780h 96 Tests
EUR 824

Human Nuclear pore complex protein Nup93, NUP93 ELISA KIT
ELI-36781h 96 Tests
EUR 824

Human Nuclear pore complex protein Nup107, NUP107 ELISA KIT
ELI-36840h 96 Tests
EUR 824

Nuclear Pore Complex-Interacting Protein-Like 2 (NPIPL2) Antibody
abx034938-400ul 400 ul
EUR 523

Nuclear Pore Complex-Interacting Protein-Like 2 (NPIPL2) Antibody
abx034938-80l 80 µl
EUR 286

Human Nuclear pore complex protein Nup98- Nup96, NUP98 ELISA KIT
ELI-13775h 96 Tests
EUR 824

ELISA kit for Rat Nuclear pore complex protein Nup153 (NUP153)
KTE100879-48T 48T
EUR 332
Description: Quantitative sandwich ELISA for measuring Rat Nuclear pore complex protein Nup153 (NUP153) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Rat Nuclear pore complex protein Nup153 (NUP153)
KTE100879-5platesof96wells 5 plates of 96 wells
EUR 2115
Description: Quantitative sandwich ELISA for measuring Rat Nuclear pore complex protein Nup153 (NUP153) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Rat Nuclear pore complex protein Nup153 (NUP153)
KTE100879-96T 96T
EUR 539
Description: Quantitative sandwich ELISA for measuring Rat Nuclear pore complex protein Nup153 (NUP153) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Recombinant Human Nuclear pore complex protein Nup153 Protein, His, E.coli-100ug
QP6439-ec-100ug 100ug
EUR 408

Recombinant Human Nuclear pore complex protein Nup153 Protein, His, E.coli-10ug
QP6439-ec-10ug 10ug
EUR 200

Recombinant Human Nuclear pore complex protein Nup153 Protein, His, E.coli-1mg
QP6439-ec-1mg 1mg
EUR 1632

Recombinant Human Nuclear pore complex protein Nup153 Protein, His, E.coli-200ug
QP6439-ec-200ug 200ug
EUR 634

Recombinant Human Nuclear pore complex protein Nup153 Protein, His, E.coli-500ug
QP6439-ec-500ug 500ug
EUR 1060

Recombinant Human Nuclear pore complex protein Nup153 Protein, His, E.coli-50ug
QP6439-ec-50ug 50ug
EUR 263

SEC13 Homolog, Nuclear Pore And COPII Coat Complex Component (SEC13) Antibody
20-abx126518
  • EUR 411.00
  • EUR 592.00
  • EUR 182.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

SEC13 Homolog, Nuclear Pore And COPII Coat Complex Component (SEC13) Antibody
20-abx123660
  • EUR 411.00
  • EUR 592.00
  • 100 ul
  • 200 ul

SEC13 Homolog, Nuclear Pore And COPII Coat Complex Component (SEC13) Antibody
abx025879-400ul 400 ul
EUR 523

SEC13 Homolog, Nuclear Pore And COPII Coat Complex Component (SEC13) Antibody
abx025879-80l 80 µl
EUR 286

SEC13 Homolog, Nuclear Pore And COPII Coat Complex Component (SEC13) Antibody
abx237677-100ug 100 ug
EUR 509

Nuclear pore membrane glycoprotein 210 Antibody
20-abx110055
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Recombinant rat Nuclear pore glycoprotein p62
P1858 100ug Ask for price
Description: Recombinant protein for rat Nuclear pore glycoprotein p62

Human SEC13 Homolog, Nuclear Pore And COPII Coat Complex Component (SEC13) ELISA Kit
abx383083-96tests 96 tests
EUR 911

Human Nuclear pore membrane glycoprotein 210 (NUP210)
1-CSB-EP016195HU(C)
  • EUR 380.00
  • EUR 214.00
  • EUR 1309.00
  • EUR 560.00
  • EUR 873.00
  • EUR 262.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Human Nuclear pore membrane glycoprotein 210(NUP210),partial expressed in E.coli

Human Nuclear pore membrane glycoprotein 210 (NUP210)
1-CSB-EP016195HU(N)
  • EUR 380.00
  • EUR 214.00
  • EUR 1309.00
  • EUR 560.00
  • EUR 873.00
  • EUR 262.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Human Nuclear pore membrane glycoprotein 210(NUP210),partial expressed in E.coli

Nuclear pore membrane glycoprotein 210 Antibody (Biotin)
20-abx105729
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Nuclear pore membrane glycoprotein 210 Antibody (FITC)
20-abx107147
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Nuclear pore membrane glycoprotein 210 Antibody (HRP)
20-abx108568
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Nuclear Pore Associated Protein 1 (NPAP1) Antibody
20-abx339916
  • EUR 411.00
  • EUR 300.00
  • 100 ul
  • 50 ul

Nuclear Pore Associated Protein 1 (NPAP1) Antibody
20-abx339917
  • EUR 411.00
  • EUR 300.00
  • 100 ul
  • 50 ul

Nuclear pore membrane glycoprotein 210 Polyclonal Antibody
42276-100ul 100ul
EUR 333

Rabbit anti-Nuclear pore glycoprotein p62 antiserum
NUP6211-S 100 ul
EUR 457

Human Nuclear pore glycoprotein p62, NUP62 ELISA KIT
ELI-22574h 96 Tests
EUR 824

Mouse Nuclear pore glycoprotein p62, Nup62 ELISA KIT
ELI-38235m 96 Tests
EUR 865

Nuclear Pore Membrane Glycoprotein 210-Like (NUP210L) Antibody
20-abx121185
  • EUR 300.00
  • EUR 439.00
  • EUR 189.00
  • 100 ul
  • 200 ul
  • 30 ul

Nuclear Pore Membrane Glycoprotein 210-Like (NUP210L) Antibody
20-abx217285
  • EUR 425.00
  • EUR 342.00
  • 100 ug
  • 50 ug

Nuclear pore membrane glycoprotein 210 Polyclonal Conjugated Antibody
C42276 100ul
EUR 397

Human Nuclear pore membrane glycoprotein 210, NUP210 ELISA KIT
ELI-19703h 96 Tests
EUR 824

Mouse Nuclear pore membrane glycoprotein 210, Nup210 ELISA KIT
ELI-45547m 96 Tests
EUR 865

Nuclear Pore-Associated Protein 60 kDa-Like (Npap60) Antibody
abx430652-200ul 200 ul
EUR 384

Control/Blocking Peptide Nuclear pore membrane glycoprotein Nup210 (GP210)
GP210-11C 100 ug
EUR 225

Rabbit anti-Nuclear pore membrane glycoprotein Nup210 (GP210) antiserum
GP210-11S 100 ul
EUR 457

Recombinant Human Nuclear pore membrane glycoprotein 210 Protein, His, E.coli-100ug
QP6440-ec-100ug 100ug
EUR 408

Recombinant Human Nuclear pore membrane glycoprotein 210 Protein, His, E.coli-10ug
QP6440-ec-10ug 10ug
EUR 200

Recombinant Human Nuclear pore membrane glycoprotein 210 Protein, His, E.coli-1mg
QP6440-ec-1mg 1mg
EUR 1632

Recombinant Human Nuclear pore membrane glycoprotein 210 Protein, His, E.coli-200ug
QP6440-ec-200ug 200ug
EUR 634

Recombinant Human Nuclear pore membrane glycoprotein 210 Protein, His, E.coli-500ug
QP6440-ec-500ug 500ug
EUR 1060

Recombinant Human Nuclear pore membrane glycoprotein 210 Protein, His, E.coli-50ug
QP6440-ec-50ug 50ug
EUR 263

ACCPA ELISA Kit| Mouse anti-cyclic citrullinated peptide antibod
EF012980 96 Tests
EUR 689

ELISA kit for Rat Nuclear envelope pore membrane protein POM 121 (POM121)
KTE100870-48T 48T
EUR 332
Description: Quantitative sandwich ELISA for measuring Rat Nuclear envelope pore membrane protein POM 121 (POM121) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Rat Nuclear envelope pore membrane protein POM 121 (POM121)
KTE100870-5platesof96wells 5 plates of 96 wells
EUR 2115
Description: Quantitative sandwich ELISA for measuring Rat Nuclear envelope pore membrane protein POM 121 (POM121) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Rat Nuclear envelope pore membrane protein POM 121 (POM121)
KTE100870-96T 96T
EUR 539
Description: Quantitative sandwich ELISA for measuring Rat Nuclear envelope pore membrane protein POM 121 (POM121) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Human anti-Nuclear pore glycoprotein p62 IgG ELISA Kit, 96 tests, Quantitative
NUP62-100 1 Kit
EUR 712

Human anti-Nuclear pore glycoprotein p62 IgM ELISA Kit, 96 tests, Quantitative
NUP62-105 1 Kit
EUR 712

Mouse anti-Nuclear pore glycoprotein p62 IgG ELISA Kit, 96 tests, Quantitative
NUP62-110 1 Kit
EUR 712

Rat anti-Nuclear pore glycoprotein p62 IgG ELISA Kit, 96 tests, Quantitative
NUP62-120 1 Kit
EUR 712

Monkey anti-Nuclear pore glycoprotein p62 IgG ELISA Kit, 96 tests, Quantitative
NUP62-130 1 Kit
EUR 712

Recombinant (E.coli) Nuclear pore glycoprotein p62 (Human, 338-522 aa, His-tag)
NUP62-N-100 100 ug
EUR 286

Lys proteins Antibody
ABD2705 100 ug
EUR 438

Lys proteins Antibody
DF2705 200ul
EUR 304
Description: Lys proteins antibody detects endogenous levels of total Lys proteins.

Bone Matrix Proteins
5-00844 4 x 5mg Ask for price

Bone Matrix Proteins
20-abx265965
  • EUR 384.00
  • EUR 592.00
  • EUR 300.00
  • 10 mg
  • 25 mg
  • 5 mg

Lys proteins Antibody
abx219526-100ug 100 ug
EUR 439

Small Nuclear RNA Activating Complex Polypeptide 5 (SNAPC5) Antibody
20-abx218687
  • EUR 425.00
  • EUR 342.00
  • 100 ug
  • 50 ug

Small Nuclear RNA Activating Complex Polypeptide 5 (SNAPC5) Antibody
abx238059-100ug 100 ug
EUR 551

Small Nuclear RNA Activating Complex Polypeptide 5 (SNAPC5) Antibody
20-abx325174
  • EUR 314.00
  • EUR 244.00
  • 100 ug
  • 50 ug

Lys proteins Blocking Peptide
DF2705-BP 1mg
EUR 195

Anti-Bovine Plasma Proteins
BPP04 1 ml
EUR 334
Description: Anti-Bovine Plasma Proteins by Cygnus Technologies is available in Europe via Gentaur.

Anti-Bovine Plasma Proteins
BPP04-AF 1 mg
EUR 1913
Description: Anti-Bovine Plasma Proteins by Cygnus Technologies is available in Europe via Gentaur.

Anti-Bovine Plasma Proteins
BPP04-PA 1 ml
EUR 488
Description: Anti-Bovine Plasma Proteins by Cygnus Technologies is available in Europe via Gentaur.

Anti-Bovine Plasma Proteins
BPP04AF-HRP 100 ul
EUR 989
Description: Anti-Bovine Plasma Proteins by Cygnus Technologies is available in Europe via Gentaur.

serum proteins kit dysproteinaemia
EHCA1200-KC30-R ea
EUR 114

Human Small Nuclear RNA Activating Complex Polypeptide 5 (SNAPC5) ELISA Kit
abx383334-96tests 96 tests
EUR 911

SNAPC1 Small Nuclear RNA Activating Complex, Polypeptide 1 Human Recombinant Protein
PROTQ16533 Regular: 20ug
EUR 317
Description: SNAPC1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 391 amino acids (1-368 a.a) and having a molecular mass of 45.4kDa.;SNAPC1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Human Tau proteins ELISA kit
CSB-E12011h-24T 1 plate of 24 wells
EUR 165
Description: Quantitativesandwich ELISA kit for measuring Human Tau proteins in samples from serum, plasma, cerebrospinalfluid (CSF). A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Human Tau proteins ELISA kit
1-CSB-E12011h
  • EUR 900.00
  • EUR 5476.00
  • EUR 2900.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Human Tau proteins in samples from serum, plasma, cerebrospinalfluid(CSF). Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Rat Tau Proteins ELISA kit
CSB-E13729r-24T 1 plate of 24 wells
EUR 165
Description: Quantitativesandwich ELISA kit for measuring Rat Tau Proteins in samples from serum, plasma, cerebrospinalfluid (CSF). A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Rat Tau Proteins ELISA kit
1-CSB-E13729r
  • EUR 900.00
  • EUR 5476.00
  • EUR 2900.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Rat Tau Proteins in samples from serum, plasma, cerebrospinalfluid(CSF). Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Goat Milk Proteins Sample Diluent
F243A 1000 ml
EUR 565
Description: Goat Milk Proteins Sample Diluent by Cygnus Technologies is available in Europe via Gentaur.

Goat Milk Proteins Sample Diluent
F243A-100 100 ml
EUR 257
Description: Goat Milk Proteins Sample Diluent by Cygnus Technologies is available in Europe via Gentaur.

Goat Milk Proteins Sample Diluent
F243A-500 500 ml
EUR 411
Description: Goat Milk Proteins Sample Diluent by Cygnus Technologies is available in Europe via Gentaur.

Goat Milk Proteins Antigen Concentrate
F243H 100 ul
EUR 411
Description: Goat Milk Proteins Antigen Concentrate by Cygnus Technologies is available in Europe via Gentaur.

Goat Milk Proteins Control Antigen
F247 50 ul
EUR 257
Description: Goat Milk Proteins Control Antigen by Cygnus Technologies is available in Europe via Gentaur.

Bovine Plasma Proteins ELISA kit
F290 1 kit (96 wells plate)
EUR 880
Description: Bovine Plasma Proteins ELISA kit by Cygnus Technologies is available in Europe via Gentaur.

Bovine Plasma Proteins Antigen Concentrate
F293G 400 ul
EUR 488
Description: Bovine Plasma Proteins Antigen Concentrate by Cygnus Technologies is available in Europe via Gentaur.

Acetyl Lys proteins Polyclonal Antibody
ES4384-100ul 100ul
EUR 279
Description: A Rabbit Polyclonal antibody against Acetyl Lys proteins from Human/Mouse/Rat/Monkey. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA

Acetyl Lys proteins Polyclonal Antibody
ES4384-50ul 50ul
EUR 207
Description: A Rabbit Polyclonal antibody against Acetyl Lys proteins from Human/Mouse/Rat/Monkey. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA

Acetyl Lys proteins Polyclonal Antibody
ABP53385-003ml 0.03ml
EUR 158
Description: A polyclonal antibody for detection of Acetyl Lys proteins from Human, Mouse, Rat, Monkey. This Acetyl Lys proteins antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human acetylation Lys proteins

Acetyl Lys proteins Polyclonal Antibody
ABP53385-01ml 0.1ml
EUR 289
Description: A polyclonal antibody for detection of Acetyl Lys proteins from Human, Mouse, Rat, Monkey. This Acetyl Lys proteins antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human acetylation Lys proteins

Acetyl Lys proteins Polyclonal Antibody
ABP53385-02ml 0.2ml
EUR 414
Description: A polyclonal antibody for detection of Acetyl Lys proteins from Human, Mouse, Rat, Monkey. This Acetyl Lys proteins antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human acetylation Lys proteins

Anti-Total Goat Milk Proteins
4042 1 ml
EUR 334
Description: Anti-Total Goat Milk Proteins by Cygnus Technologies is available in Europe via Gentaur.

Anti-Total Goat Milk Proteins
4042-AF 1 mg
EUR 1913
Description: Anti-Total Goat Milk Proteins by Cygnus Technologies is available in Europe via Gentaur.

Anti-Total Goat Milk Proteins
4042-PA 1 ml
EUR 488
Description: Anti-Total Goat Milk Proteins by Cygnus Technologies is available in Europe via Gentaur.

Chicken Egg white proteins total
CEGW15-N 10 mg
EUR 408

Chicken Egg yellow proteins total
CEYP17-N 10 mg
EUR 225

Mitochondrial Permeability Transition Pore Assay Kit
K239-100
EUR 544

Mitochondrial Permeability Transition Pore Assay Kit
K2061-100 100 assays
EUR 614

E Coli proteins (5 strains) host cell proteins (HCPs) ELISA kit, 96 tests
800-130-ECP 1 Kit
EUR 834

Rabbit Anti-E. Coli Proteins IgG-Agarose affinity gel for removing E. coli proteins
EC12-AS 1 ml
EUR 529

Plant Pathogenesis- related proteins ELISA Kit
ELA-E0431Pl 96 Tests
EUR 928

Bovine bone morphogenetic proteins ELISA Kit
ELA-E0653b 96 Tests
EUR 928

Human bone morphogenetic proteins ELISA Kit
ELA-E0653h 96 Tests
EUR 824

Rabbit bone morphogenetic proteins ELISA Kit
ELA-E0653Rb 96 Tests
EUR 928

CHO Host Cell Proteins Elisa kit
E4537-100
EUR 1023

Human Opacity associated proteins ELISA kit
E01O0315-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Human Opacity associated proteins in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Opacity associated proteins ELISA kit
E01O0315-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Human Opacity associated proteins in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Opacity associated proteins ELISA kit
E01O0315-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Human Opacity associated proteins in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Bone morphogenetic proteins ELISA kit
E01B0682-192T 192 tests
EUR 1270
Description: A competitive for quantitative measurement of Human Bone morphogenetic proteins in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Bone morphogenetic proteins ELISA kit
E01B0682-48 1 plate of 48 wells
EUR 520
Description: A competitive for quantitative measurement of Human Bone morphogenetic proteins in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Bone morphogenetic proteins ELISA kit
E01B0682-96 1 plate of 96 wells
EUR 685
Description: A competitive for quantitative measurement of Human Bone morphogenetic proteins in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Crystal proteins a ELISA kit
E01C0827-192T 192 tests
EUR 1270
Description: A sandwich ELISA for quantitative measurement of Human Crystal proteins a in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Crystal proteins a ELISA kit
E01C0827-48 1 plate of 48 wells
EUR 520
Description: A sandwich ELISA for quantitative measurement of Human Crystal proteins a in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Crystal proteins a ELISA kit
E01C0827-96 1 plate of 96 wells
EUR 685
Description: A sandwich ELISA for quantitative measurement of Human Crystal proteins a in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Crystal proteins β ELISA kit
E01C0828-192T 192 tests
EUR 1270
Description: A sandwich ELISA for quantitative measurement of Human Crystal proteins β in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Crystal proteins β ELISA kit
E01C0828-48 1 plate of 48 wells
EUR 520
Description: A sandwich ELISA for quantitative measurement of Human Crystal proteins β in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Crystal proteins β ELISA kit
E01C0828-96 1 plate of 96 wells
EUR 685
Description: A sandwich ELISA for quantitative measurement of Human Crystal proteins β in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Bone morphogenetic proteins ELISA kit
E02B0682-192T 192 tests
EUR 1270
Description: A competitive for quantitative measurement of Rat Bone morphogenetic proteins in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Bone morphogenetic proteins ELISA kit
E02B0682-48 1 plate of 48 wells
EUR 520
Description: A competitive for quantitative measurement of Rat Bone morphogenetic proteins in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Bone morphogenetic proteins ELISA kit
E02B0682-96 1 plate of 96 wells
EUR 685
Description: A competitive for quantitative measurement of Rat Bone morphogenetic proteins in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Opacity associated proteins ELISA kit
E03O0314-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Mouse Opacity associated proteins in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Opacity associated proteins ELISA kit
E03O0314-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Mouse Opacity associated proteins in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Opacity associated proteins ELISA kit
E03O0314-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Mouse Opacity associated proteins in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Bone morphogenetic proteins ELISA kit
E03B0682-192T 192 tests
EUR 1270
Description: A competitive for quantitative measurement of Mouse Bone morphogenetic proteins in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Bone morphogenetic proteins ELISA kit
E03B0682-48 1 plate of 48 wells
EUR 520
Description: A competitive for quantitative measurement of Mouse Bone morphogenetic proteins in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Bone morphogenetic proteins ELISA kit
E03B0682-96 1 plate of 96 wells
EUR 685
Description: A competitive for quantitative measurement of Mouse Bone morphogenetic proteins in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Crystal proteins a ELISA kit
E03C0827-192T 192 tests
EUR 1270
Description: A sandwich ELISA for quantitative measurement of Mouse Crystal proteins a in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Crystal proteins a ELISA kit
E03C0827-48 1 plate of 48 wells
EUR 520
Description: A sandwich ELISA for quantitative measurement of Mouse Crystal proteins a in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Crystal proteins a ELISA kit
E03C0827-96 1 plate of 96 wells
EUR 685
Description: A sandwich ELISA for quantitative measurement of Mouse Crystal proteins a in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Crystal proteins β ELISA kit
E03C0828-192T 192 tests
EUR 1270
Description: A sandwich ELISA for quantitative measurement of Mouse Crystal proteins β in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Crystal proteins β ELISA kit
E03C0828-48 1 plate of 48 wells
EUR 520
Description: A sandwich ELISA for quantitative measurement of Mouse Crystal proteins β in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Crystal proteins β ELISA kit
E03C0828-96 1 plate of 96 wells
EUR 685
Description: A sandwich ELISA for quantitative measurement of Mouse Crystal proteins β in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Opacity associated proteins ELISA kit
E02O0314-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Rat Opacity associated proteins in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Opacity associated proteins ELISA kit
E02O0314-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Rat Opacity associated proteins in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Opacity associated proteins ELISA kit
E02O0314-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Rat Opacity associated proteins in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Bone morphogenetic proteins ELISA kit
E04B0682-192T 192 tests
EUR 1270
Description: A competitive for quantitative measurement of Rabbit Bone morphogenetic proteins in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Bone morphogenetic proteins ELISA kit
E04B0682-48 1 plate of 48 wells
EUR 520
Description: A competitive for quantitative measurement of Rabbit Bone morphogenetic proteins in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Bone morphogenetic proteins ELISA kit
E04B0682-96 1 plate of 96 wells
EUR 685
Description: A competitive for quantitative measurement of Rabbit Bone morphogenetic proteins in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Crystal proteins a ELISA kit
E04C0827-192T 192 tests
EUR 1270
Description: A sandwich ELISA for quantitative measurement of Rabbit Crystal proteins a in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Crystal proteins a ELISA kit
E04C0827-48 1 plate of 48 wells
EUR 520
Description: A sandwich ELISA for quantitative measurement of Rabbit Crystal proteins a in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
These knowledge point out a possible tumor-suppressive perform of TMEM88 in thyroid most cancers. Our research highlights a key position for TMEM88 in regulating Wnt/β-catenin signaling throughout the development of thyroid most cancers and means that TMEM88 is a pretty anticancer goal for thyroid most cancers.